Shkëndija defeated FCSB 1-0 in the first leg of the UEFA Champions League second qualifying round at National Arena Todor Proeski Skopje on July 22, 2025.

The decisive goal came in the second half when Shkëndija converted their lone shot on target. FCSB received one yellow card during the match.

Shkëndija registered 9 total attempts with 8 blocks by FCSB defenders, while FCSB failed to score despite their offensive efforts.

The second leg will be played on July 30, 2025, at Arena Națională in Bucharest, with FCSB needing to overturn the 1-0 deficit.